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CD34+ Hematopoietic Stem Cells |
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| CD34,
a single-pass type I transmembrane glycoprotein, is typically expressed on lymphohematopoietic stem and progenitor cells. CD34+ fractions enriched from human cord blood are up to 100-fold enriched in various colony forming units (CFUs), including CFU-blast, CFU-macrophage, CFU-granulocyte as well as burst forming-erythroid (BFU-E). In vivo and in vitro, as these cells mature and differentiate, the level of CD34 expression on the cell surface decreases. CD34+ cells are capable of maintaining long-term hematopoiesis. Current methodologies utilizing CD34+ enriched fractions from human cord blood include ex vivo genetic modification, transplant and engraftment studies, graft versus host disease studies, drug resistance gene delivery anticancer vaccination research, as well as toxicological testing.
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Ordering Information
THESE PRODUCTS ARE FOR RESEARCH USE
ONLY. Not approved for human or veterinary
use, for application to humans or animals, or for in vitro diagnostic or clinical procedures. |
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